Fibronectin Antibody, IgG1, Clone: [Fn-3], Mouse, Monoclonal

Produktübersicht

• Artikelname: Fibronectin Antibody, IgG1, Clone: [Fn-3], Mouse, Monoclonal
• Artikelnummer: NBT-2335-MSM7-P1
• Hersteller Artikelnummer: 2335-MSM7-P1
• Alternativnummer: NBT-2335-MSM7-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FC, IF, IHC
• Spezies Reaktivität: Human
• Immunogen: FR5 cells, derived by SV40 transformation of human mammary epithelial cells.
• Alternative Synonym: Cold insoluble globulin (CIG), FINC, FN1, FNZ, GFND, GFND2, LETS, Migration stimulating factor (MSF), Ugl-Y3

Produktbeschreibung

Fibronectins are disulfide-linked, dimeric glycoproteins of ~440kDa. They possess at least four binding sites for collagen, glycosaminoglycans, transglutaminase, and a cell surface receptor. Epitope of this MAb is located in the 2nd-3rd type-III repeats of fibronectin. Fibronectins are extracellular matrix glycoproteins that are essential for embryonic development. Fibronectins are also involved in cell adhesion, tissue organization, and wound healing. Fibronectins are present in basement membranes, interstitial connective tissue matrix, and blood. Cellular fibronectin is widely distributed in the stroma of many malignant tumors. This MAb reacts with human cellular fibronectin, but not plasma fibronectin.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [Fn-3]
• Molekulargewicht: 220kDa (monomer), 440kDa (dimer)
• Isotyp: IgG1
• NCBI: 2335
• UniProt: P02751
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

SDS-PAGE Analysis of Purified Fibronectin Mouse Monoclonal Antibody (Fn-3). Confirmation of Integrity and Purity of Antibody.