Recombinant Frataxin (Mitochondrial Marker) Antibody, IgG1, Clone: [rFXN/2124], Mouse, Monoclonal

Produktübersicht

• Artikelname: Recombinant Frataxin (Mitochondrial Marker) Antibody, IgG1, Clone: [rFXN/2124], Mouse, Monoclonal
• Artikelnummer: NBT-2395-MSM6-P1
• Hersteller Artikelnummer: 2395-MSM6-P1
• Alternativnummer: NBT-2395-MSM6-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: ELISA
• Spezies Reaktivität: Human
• Immunogen: Recombinant human Frataxin protein fragment (around aa 57-210) (exact sequence is proprietary)
• Alternative Synonym: CyaY, d-FXN, FARR, Frataxin mature form, Frataxin (81-210), FRDA, Friedreich ataxia protein, Fxn, i-FXN, m56-FXN, m78-FXN, m81-FXN, X25

Produktbeschreibung

Frataxin is a nuclear-encoded mitochondrial protein implicated in Friedreichs ataxia (FRDA), a human autosomal recessive neurodegenerative disease. Lack of Frataxin causes iron to accumulate in the mitochondrial matrix suggesting that Frataxin is involved in mitochondrial iron homeostasis and possibly in iron transport. Frataxin has an alpha-beta fold consisting of two helices flanking an antiparallel beta sheet.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [rFXN/2124]
• Molekulargewicht: 14kDa
• Isotyp: IgG1
• NCBI: 2395
• UniProt: Q16595
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

SDS-PAGE Analysis of Purified Frataxin Recombinant Mouse Monoclonal Antibody (rFXN/2124). Confirmation of Purity and Integrity of Antibody.