Recombinant NKX2.8 Antibody, Clone: [NKX28/3233R], Rabbit, Monoclonal

Produktübersicht

• Artikelname: Recombinant NKX2.8 Antibody, Clone: [NKX28/3233R], Rabbit, Monoclonal
• Artikelnummer: NBT-26257-RBM7-P1
• Hersteller Artikelnummer: 26257-RBM7-P1
• Alternativnummer: NBT-26257-RBM7-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA
• Spezies Reaktivität: Human
• Immunogen: Human recombinant NKX2.8 protein fragment (around aa 10-123) (exact sequence is proprietary)
• Alternative Synonym: Homeobox protein NK-2 homolog H, NK2 homeobox 8, NK2 transcription factor related, locus 8, Nkx2 9, Nkx2-8, NKX2.8, NKX2G, NKX2H, OTTHUMP00000027959

Produktbeschreibung

The protein encoded by this gene is a homeobox-containing developmental regulator associated with liver development. The encoded protein binds to the alpha-fetoprotein (AFP) gene promoter and increases the expression of AFP. This gene is overexpressed in some lung cancers and is linked to poor patient survival, possibly due to its resistance to cisplatin. This gene is aberrantly methylated in pancreatic cancer, deleted in squamous cell lung carcinomas, and acts as a tumor suppressor in esophageal cancer. Mutations in this gene may also be a cause of neural tube defects.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [NKX28/3233R]
• Molekulargewicht: 26kDa
• NCBI: 26257
• UniProt: O15522
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Western Blot Analysis of PC3 and MCF-7 cell lysate using NKX2.8 Recombinant Rabbit Monoclonal Antibody (NKX28/3233R).