Blood Group Antigen A (CD173) Antibody, IgM, Clone: [HE-193], Mouse, Monoclonal

Produktübersicht

• Artikelname: Blood Group Antigen A (CD173) Antibody, IgM, Clone: [HE-193], Mouse, Monoclonal
• Artikelnummer: NBT-28-MSM5-P1BX
• Hersteller Artikelnummer: 28-MSM5-P1BX
• Alternativnummer: NBT-28-MSM5-P1BX-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IF, IHC
• Spezies Reaktivität: Human
• Immunogen: Mixture of erythrocytes of blood group Aand glycoprotein fraction isolated from the saliva of secretors with blood group A
• Alternative Synonym: A transferase, ABO, B transferase, CD173, Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, Histo-blood group A transferase, Histo-blood group B transferase, NAGAT

Produktbeschreibung

This antibody recognizes human blood group A (monofucosyl and difucosyl A antigens with chain types 1, 2, 3, 4, 5, 6) and Forssmann antigen. Blood-group antigens are generally defined as molecules formed by sequential addition of saccharides to the carbohydrate side chains of lipids and proteins detected on erythrocytes and certain epithelial cells. The A, B and H antigens are reported to undergo modulation during malignant cellular transformation. Blood group related antigens represent a group of carbohydrate determinants carried on both glycolipids and glycoproteins. They are usually mucin-type, and are detected on erythrocytes, certain epithelial cells, and in secretions of certain individuals. Sixteen genetically and biosynthetically distinct but inter-related specificities belong to this group of antigens, including A, B, H, Lewis A, Lewis B, Lewis X, Lewis Y, and precursor type 1 chain antigens.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [HE-193]
• Molekulargewicht: Multiple
• Isotyp: IgM
• NCBI: 28
• UniProt: P16442
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Formalin-paraffin human Colon Carcinoma stained with Blood Group Antigen A Mouse MAb (HE-193)