Recombinant PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) Antibody, IgG1, Clone: [rPDL1/8825], Mouse, Monoclonal

Produktübersicht

• Artikelname: Recombinant PD-L1 / PDCD1LG1 / CD274 / B7-H1 (Cancer Immunotherapy Target) Antibody, IgG1, Clone: [rPDL1/8825], Mouse, Monoclonal
• Artikelnummer: NBT-29126-MSM31-P0
• Hersteller Artikelnummer: 29126-MSM31-P0
• Alternativnummer: NBT-29126-MSM31-P0-20
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment (around aa190-290) of human CD274 protein (exact sequence is proprietary)
• Alternative Synonym: B7 homolog 1, B7-H1, CD274, PD-L1, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, Programmed cell death 1 ligand 1

Produktbeschreibung

PD-L1 is a checkpoint regulator in immune cells, it is expressed on immune or non-hematopoietic cells. Expression of the protein is seen during pregnancy where it has a role in suppressing the immune system. PD-L1 induces an inhibitory signal in activated T-cells and promotes T-cell apoptosis. It is overexpressed in a number of different cancers where it is believed to play a significant role in the cancer s ability to evade the immune system.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [rPDL1/8825]
• Molekulargewicht: 37-50kDa
• Isotyp: IgG1
• NCBI: 29126
• UniProt: Q9NZQ7
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

SDS-PAGE Analysis of Purified PD-L1 Recombinant Mouse Monoclonal Antibody (rPDL1/8825). Confirmation of Purity and Integrity of Antibody.