Recombinant Annexin A1 / (Hairy Cell Leukemia Marker) Antibody, Clone: [ANXA1/3869R], Rabbit, Monoclonal

Produktübersicht

• Artikelname: Recombinant Annexin A1 / (Hairy Cell Leukemia Marker) Antibody, Clone: [ANXA1/3869R], Rabbit, Monoclonal
• Artikelnummer: NBT-301-RBM9-P1
• Hersteller Artikelnummer: 301-RBM9-P1
• Alternativnummer: NBT-301-RBM9-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human, Mouse
• Immunogen: Recombinant full-length human Annexin A1 protein
• Alternative Synonym: ANXA1, ANX1, Annexin-1, Chromobindin-9, LPC1, p35

Produktbeschreibung

The ANXA1 gene belongs to the annexin family, and contains 4 annexin repeats. A pair of annexin repeats may form one binding site for calcium and a phospholipid. ANXA1 promotes membrane fusion and is involved in exocytosis. The gene for ANXA1 is upregulated in hairy cell leukemia (HCL), and its protein expression is specific for HCL. Detection of ANXA1 provides a simple, highly sensitive and specific assay for diagnosing HCL. Annexin A1 has also been found to be protective against DNA damage induced by heat in breast cancer cells, suggesting it is involved in tumor suppressive and protective activities, and also is associated with treatment resistance.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [ANXA1/3869R]
• Molekulargewicht: 38kDa
• NCBI: 301
• UniProt: P04083
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

West

Formalin-fixed, paraffin-embedded human tonsil stained with Annexin A1 Recombinant Rabbit Monoclonal Antibody (ANXA1/3869R).

Formalin-fixed, paraffin-embedded human tonsil stained with Annexin A1 Recombinant Rabbit Monoclonal Antibody (ANXA1/3869R).

Western Blot Analysis of A549 cell lysate using Annexin A1 Recombinant Rabbit Monoclonal Antibody (ANXA1/3869R).

Western Blot Analysis of A549 lysate using Annexin A1 Rabbit Recombinant Monoclonal Antibody (ANXA1/3869R).

SDS-PAGE Analysis Purified Annexin A1 Recombinant Rabbit Monoclonal Antibody (ANXA1/3869R ). Confirmation of Purity and Integrity of Antibody.

Western Blot Analysis of Human Intestine and Human Lung tissue lysates using Annexin A1 Recombinant Rabbit Monoclonal Antibody (ANXA1/3869R).

Western Blot Analysis of Intestine and Lung tissue lysates of different species using Annexin A1 Recombinant Rabbit Monoclonal Antibody (ANXA1/3869R).