HLA-DRB (MHC II) Antibody, IgG2a, Clone: [Bra30], Mouse, Monoclonal

Artikelnummer: NBT-3123-MSM4-P1ABX
Artikelname: HLA-DRB (MHC II) Antibody, IgG2a, Clone: [Bra30], Mouse, Monoclonal
Artikelnummer: NBT-3123-MSM4-P1ABX
Hersteller Artikelnummer: 3123-MSM4-P1ABX
Alternativnummer: NBT-3123-MSM4-P1ABX-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: FC, IF
Spezies Reaktivität: Canine, Human, Monkey, Primate, Rodent
Immunogen: Human REH cells (non-T, non-B leukemia cell line)
Alternative Synonym: HLA class II histocompatibility antigen DR beta 3 chain, HLADR3B, Major histocompatibility complex, class II DR beta 3
This MAb reacts with the HLA-DRB3 antigen, a member of MHC class II molecules.It does not cross react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36kDa alpha (heavy) chain and a 28kDa beta (light) chain. It is expressed on B-cells, activated T-cells, monocytes/macrophages, dendritic cells and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. HLA-DR antigens also occur on a variety of epithelial cells and their corresponding neoplastic counterparts.
Klonalität: Monoclonal
Klon-Bezeichnung: [Bra30]
Molekulargewicht: ~28kDa (beta chain)
Isotyp: IgG2a
NCBI: 3123
UniProt: P01911
Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Monoclonal Antibody
Anwendungsbeschreibung: Flow Cytometry (1-2ug/million cells), Immunofluorescence (1-2ug/ml), Optimal dilution for a specific application should be determined.
SDS-PAGE Analysis of Purified HLA-DRB Mouse Monoclonal Antibody (BRA30).Confirmation of Purity and Integrity of Antibody.