CD50 / ICAM3 Antibody, IgG2b, Clone: [186-2G9], Mouse, Monoclonal

Artikelnummer: NBT-3385-MSM1-P0
Artikelname: CD50 / ICAM3 Antibody, IgG2b, Clone: [186-2G9], Mouse, Monoclonal
Artikelnummer: NBT-3385-MSM1-P0
Hersteller Artikelnummer: 3385-MSM1-P0
Alternativnummer: NBT-3385-MSM1-P0-20,NBT-3385-MSM1-P0-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: IF, IHC
Spezies Reaktivität: Human
Immunogen: Stimulated human leukocytes
Alternative Synonym: ICAMR, Intercellular adhesion molecule 3 (ICAM3)
Recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (Leucocyte Workshop VI). CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion.
Klonalität: Monoclonal
Klon-Bezeichnung: [186-2G9]
Molekulargewicht: 110-160kDa
Isotyp: IgG2b
NCBI: 3385
UniProt: P32942
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Monoclonal Antibody
Anwendungsbeschreibung: Blocks binding of CD11a (LFA-1) to CD50 (ICAM-3) (Order Ab without Azide),Immunofluorescence (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tri