Recombinant CD50 / ICAM3 Antibody, Clone: [ICAM3/2873R], Rabbit, Monoclonal

Artikelnummer: NBT-3385-RBM6-P0
Artikelname: Recombinant CD50 / ICAM3 Antibody, Clone: [ICAM3/2873R], Rabbit, Monoclonal
Artikelnummer: NBT-3385-RBM6-P0
Hersteller Artikelnummer: 3385-RBM6-P0
Alternativnummer: NBT-3385-RBM6-P0-20,NBT-3385-RBM6-P0-100
Hersteller: NeoBiotechnologies
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human
Immunogen: Recombinant full-length human ICAM3 protein
Alternative Synonym: CD50, CDW 50, CDw50, ICAM 3, ICAM-3, ICAM-R, ICAM3, ICAM3_HUMAN, ICAMR, Intercellular adhesion molecule 3
Recognizes the D1 domain of an N-glycosylated glycoprotein of 120kDa with intra-chain disulfide bonds, identified as CD50 or ICAM-3 (Leucocyte Workshop VI). CD50 is the major ligand for LFA-1 (CD11a/CD18) and may have signaling role to increase adhesion.
Klonalität: Monoclonal
Klon-Bezeichnung: [ICAM3/2873R]
Molekulargewicht: 110-160kDa
NCBI: 3385
UniProt: P32942
Formulierung: 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Recombinant Monoclonal Antibody
Anwendungsbeschreibung: Blocks binding of CD11a (LFA-1) to CD50 (ICAM-3) (Order Ab without Azide), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 4