Recombinant IDH1-R132H (Isocitrate Dehydrogenase) Antibody, Clone: [IDH1/7277R], Rabbit, Monoclonal

Produktübersicht

• Artikelname: Recombinant IDH1-R132H (Isocitrate Dehydrogenase) Antibody, Clone: [IDH1/7277R], Rabbit, Monoclonal
• Artikelnummer: NBT-3417-RBM7-P0
• Hersteller Artikelnummer: 3417-RBM7-P0
• Alternativnummer: NBT-3417-RBM7-P0-20,NBT-3417-RBM7-P0-100
• Hersteller: NeoBiotechnologies
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment of human IDH1 (exact sequence is proprietary)
• Alternative Synonym: Cytosolic NADP-isocitrate dehydrogenase, Epididymis luminal protein 216, Epididymis secretory protein Li 26, HEL-216, HEL-S-26, ICDH, IDCD, IDH1, IDP, IDPC, Isocitrate dehydrogenase 1 (NADP+) soluble, NADP dependent isocitrate dehydrogenase peroxisomal,

Produktbeschreibung

IDH1 R132H antibody binds to IDH1-mutated protein, but does not bind the wild-type IDH1 protein. IDH1 R132H point mutations are frequently seen in World Health Organization grade II and III gliomas and are believed to constitute an early step in tumorige

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [IDH1/7277R]
• Molekulargewicht: 45-47kDa
• NCBI: 3417
• UniProt: O75874
• Formulierung: 200ug/ml of Ab produced in HEK293 cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Recombinant Monoclonal Antibody

Anwendungsbeschreibung

• Anwendungsbeschreibung: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),Optimal dilutio