HSD17B13 / Hydroxysteroid 17-beta dehydrogenase 13 (NAFLD / NASH Marker) Antibody, IgG2b, Clone: [HSD17B13/13101], Mouse, Monoclonal

Produktübersicht

• Artikelname: HSD17B13 / Hydroxysteroid 17-beta dehydrogenase 13 (NAFLD / NASH Marker) Antibody, IgG2b, Clone: [HSD17B13/13101], Mouse, Monoclonal
• Artikelnummer: NBT-345275-MSM1-P1ABX
• Hersteller Artikelnummer: 345275-MSM1-P1ABX
• Alternativnummer: NBT-345275-MSM1-P1ABX-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment (around aa1-200) of human HSD17B13 protein (exact sequence is proprietary)
• Alternative Synonym: 7-beta hydroxysteroid dehydrogenase, 17-beta-HSD 13, hepatic retinol/retinal dehydrogenase, short chain dehydrogenase/reductase family 16C member 3, short-chain dehydrogenase/reductase 9

Produktbeschreibung

Hydroxysteroid 17-beta dehydrogenase 13 (HSD17B13) is an enzyme in the liver that is associated with lipid droplets. It is encoded by the HSD17B13 gene in humans. HSD17B13 levels increase in patients with non-alcoholic fatty liver disease (NAFLD) and can enhance lipogenesis. However, some studies have shown that loss-of-function variants in HSD17B13 may protect against the progression of NAFLD to non-alcoholic steatohepatitis, fibrosis, and hepatocellular carcinoma.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [HSD17B13/13101]
• Molekulargewicht: 30kDa
• Isotyp: IgG2b
• NCBI: 345275
• UniProt: Q7Z5P4
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.