Kappa Light Chain (B-Cell Marker) Antibody, IgG1, Clone: [L1C1], Mouse, Monoclonal

Produktübersicht

• Artikelname: Kappa Light Chain (B-Cell Marker) Antibody, IgG1, Clone: [L1C1], Mouse, Monoclonal
• Artikelnummer: NBT-3514-MSM1-P1
• Hersteller Artikelnummer: 3514-MSM1-P1
• Alternativnummer: NBT-3514-MSM1-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human
• Immunogen: Human B-Lymphoma Cells
• Alternative Synonym: HCAK1, Ig Kappa Chain C Region, IGKC, Immunoglobulin KM

Produktbeschreibung

This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of kappa to lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [L1C1]
• Molekulargewicht: ~22.5kDa
• Isotyp: IgG1
• NCBI: 3514
• UniProt: P01601
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Western Blot Analysis of Raji cell lysate using Kappa Light Chain Mouse Monoclonal Antibody (L1C1).

SDS-PAGE Analysis of Purified Kappa Light