Lambda Light Chain (B-Cell Marker) Antibody, IgG1, Clone: [LAM03], Mouse, Monoclonal

Produktübersicht

• Artikelname: Lambda Light Chain (B-Cell Marker) Antibody, IgG1, Clone: [LAM03], Mouse, Monoclonal
• Artikelnummer: NBT-3535-MSM4-P1
• Hersteller Artikelnummer: 3535-MSM4-P1
• Alternativnummer: NBT-3535-MSM4-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: ELISA
• Spezies Reaktivität: Human
• Immunogen: Purified human lambda light chain
• Alternative Synonym: Bence Jones Protein, BJP, IGLC 1/2/3, Mcg Marker, Paraprotein

Produktbeschreibung

This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [LAM03]
• Molekulargewicht: ~22.5kDa
• Isotyp: IgG1
• NCBI: 3535
• UniProt: P01701
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

SDS-PAGE Analysis of Purified Lambda Light Chain Mouse Monoclonal Antibody (LAM03). Confirmation of Integrity and Purity of Antibody