Recombinant Lambda Light Chain (B-Cell Marker) Antibody, Clone: [IGL/3886R], Rabbit, Monoclonal

Artikelnummer: NBT-3535-RBM14-P1ABX
Artikelname: Recombinant Lambda Light Chain (B-Cell Marker) Antibody, Clone: [IGL/3886R], Rabbit, Monoclonal
Artikelnummer: NBT-3535-RBM14-P1ABX
Hersteller Artikelnummer: 3535-RBM14-P1ABX
Alternativnummer: NBT-3535-RBM14-P1ABX-100
Hersteller: NeoBiotechnologies
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA
Spezies Reaktivität: Human
Immunogen: Recombinant full-length human IGL protein
Alternative Synonym: Bence Jones Protein, BJP, IGLC 1/2/3, Mcg Marker, Paraprotein
This MAb is specific to lambda light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the lambda light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkins lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Klonalität: Monoclonal
Klon-Bezeichnung: [IGL/3886R]
Molekulargewicht: ~22.5kDa
NCBI: 3535
UniProt: P01701
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis Lambda LC Recombinant Rabbit Monoclonal Antibody (IGL/3886R). Confirmation of Integrity and Purity of Antibody.