Prostate Specific Antigen (PSA) Antibody, IgG1, Clone: [KLK3/801 + KLK3/1248], Mouse, Monoclonal

Produktübersicht

• Artikelname: Prostate Specific Antigen (PSA) Antibody, IgG1, Clone: [KLK3/801 + KLK3/1248], Mouse, Monoclonal
• Artikelnummer: NBT-354-MSM6-P1
• Hersteller Artikelnummer: 354-MSM6-P1
• Alternativnummer: NBT-354-MSM6-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant full-length human KLK3 protein
• Alternative Synonym: Antigen, prostate-specific (APS), Gamma-seminoprotein, hK3, Kallikrein related peptidase 3, Kallikrein-3 (KLK3), KLK2A1, P-30 antigen, Semenogelase, Seminin

Produktbeschreibung

Recognizes a single protein of 33-34kDa, identified as the prostate specific antigen (PSA). This MAb is highly specific to PSA and stains prostatic secretory and ductal epithelium in both normal and neoplastic tissues. PSA is a chymotrypsin-like serine protease (kallikrein family) exclusively produced by the prostate epithelium, and abundant in seminal fluid. PSA can be detected in the sera of patients with prostatic carcinoma. It is predominantly complexed to a liver-derived serine protease inhibitor, alpha-1-antichymotrypsin (ACT). A higher proportion of serum PSA is complexed to ACT in prostate cancer than in benign prostate hyperplasia.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [KLK3/801 + KLK3/1248]
• Molekulargewicht: 33-34kDa
• Isotyp: IgG1
• NCBI: 354
• UniProt: P07288
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with PSA Monoclonal Antibody (KLK3/801 + KLK3/1248).