Recombinant CD25 / IL2RA (Activated Lymphocyte Marker) Antibody, Clone: [IL2RA/4375R], Rabbit, Monoclonal

Produktübersicht

• Artikelname: Recombinant CD25 / IL2RA (Activated Lymphocyte Marker) Antibody, Clone: [IL2RA/4375R], Rabbit, Monoclonal
• Artikelnummer: NBT-3559-RBM9-P1
• Hersteller Artikelnummer: 3559-RBM9-P1
• Alternativnummer: NBT-3559-RBM9-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment (around aa1-250) corresponding to human IL-2 receptor alpha
• Alternative Synonym: IL2 Receptor alpha, IL2R alpha chain, IL2R, IL2R subunit alpha IL2RA, Interleukin-2 receptor subunit alpha, Ly43, p55, p55 chain, T Cell Growth Factor Receptor, TAC antigen, TCGFR

Produktbeschreibung

CD25, or interleukin 2 (IL2) receptor alpha (IL2RA), and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (CD25) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble CD25 has been isolated and determined to result from extracellular proteolysis. CD25 (the p55 chain of the interleukin-2 receptor) is a marker of activation for a number of cell types, including T cells, B cells, and macrophages. It also appears to be a reliable immunohistochemical marker for the discrimination of neoplastic from normal/reactive mast cells, with potential as a diagnostic tool in systemic mastocytosis. CD25 is also expressed on hairy cell leukemia.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [IL2RA/4375R]
• Molekulargewicht: 31kDa
• NCBI: 3559
• UniProt: P01589
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

SDS-PAGE Analysis Purified CD25 Recombinant Rabbit Monoclonal Antibody (IL2RA/4375R). Confirmation of Purity and Integrity of Antibody.