Human recombinant AQP4 protein fragment (around aa200-323) (exact sequence is proprietary)
Alternative Synonym:
WCH4, Mercurial-insensitive water channel (MIWC), HMIWC2
In skeletal muscle, AQP4 (aquaporin 4 also known as mercurial insensitive water channel), localizes to the sarcolemma of fast-twitch muscle fibers. Aquaporins (AQPs) are a large family of integral membrane water transport channel proteins that facilitate the transport of water through the cell membrane. This function is conserved in animals, plants and bacteria. Many isoforms of aquaporin have been identified in mammals, designated AQP0through AQP10. Aquaporins are widely distributed and it is not uncommon for more than one type of AQP to be present in the same cell. Although most aquaporins are only permeable to water, AQP3, AQP7, AQP9 and one of the two AQP10 transcripts are also permeable to urea and glycerol. AQP2 is the only water channel that is activated by vasopressin to enhance water reabsorption in the kidney collecting duct. Aquaporins are involved in renal water absorption, generation of pulmonary secretions, lacrimation and the secretion and reabsorption of cerebrospinal fluid and aqueous humor.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human small intestine stained wi
Formalin-fixed, paraffin-embedded human brain stained with Aquaporin (AQP4) Mouse Monoclonal Antibody (AQP4/3324). Inset: PBS instead of primary antibody, secondary only negative control.
Formalin-fixed, paraffin-embedded human small intestine stained with Aquaporin (AQP4) Mouse Monoclonal Antibody (AQP4/3324). HIER: Tris/EDTA, pH9.0, 45min. 2 °: HRP-polymer, 30min. DAB, 5min.
Formalin-fixed, paraffin-embedded human small intestine stained with Aquaporin (AQP4) Mouse Monoclonal Antibody (AQP4/3324). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.
SDS-PAGE Analysis of Purified Aquaporin (AQP4) Mouse Monoclonal Antibody (AQP4/3324). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human small intestine stained with Aquaporin (AQP4) Mouse Monoclonal Antibody (AQP4/3324). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.
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