CD11a / Integrin L / LFA-1 Chain Antibody, IgG2b, Clone: [DF1524], Mouse, Monoclonal

Produktübersicht

• Artikelname: CD11a / Integrin L / LFA-1 Chain Antibody, IgG2b, Clone: [DF1524], Mouse, Monoclonal
• Artikelnummer: NBT-3683-MSM2-P1
• Hersteller Artikelnummer: 3683-MSM2-P1
• Alternativnummer: NBT-3683-MSM2-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FC, Functional Studies, IF
• Spezies Reaktivität: Human
• Immunogen: Human CD11a protein
• Alternative Synonym: Antigen CD11A (p180), lymphocyte function associated antigen 1, alpha polypeptide, Integrin alpha-L, ITGAL, Leukocyte Adhesion Glycoprotein LFA1 Alpha Chain, LFA 1 alpha (LFA1A), Ly15, Ly21, p180

Produktbeschreibung

Recognizes a protein of 180kDa, identified as CD11a (Leucocyte Workshop IV, Code 1524). CD11a complex with the 2 subunit of the integrin family, CD18, to form the cell surface heterodimer, LFA-1 or CD11a /C18 (aLbL). LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses. This MAb potently blocks LFA-1 dependent homotypic cell aggregation.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [DF1524]
• Molekulargewicht: 180kDa
• Isotyp: IgG2b
• NCBI: 3683
• UniProt: P20701
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

SDS-PAGE Analysis of Purified CD11a Mouse Monoclonal Antibody (DF1524). Confirmation of Integrity and Purity of Antibody.