Recombinant human ARG1 protein fragment (around aa11-97) (exact sequence is proprietary)
Alternative Synonym:
Arginase 1, ARG1, liver-type arginase, type I arginase
Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes, which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Anwendungsbeschreibung:
Immunohistology (Formalin-fixed) (2-4ug/ml for 30 minutes at RT) ,(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific
Formalin-paraffin human Hepatocellular Carcinoma stained with ARG1 Mouse Monoclonal Antibody (ARG1/1125 + ARG1/1126).
Formalin-paraffin human Hepatocellular Carcinoma stained with ARG1 Mouse Monoclonal Antibody (ARG1/1125 + ARG1/1126).
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