Arginase 1 (Hepatocellular Carcinoma Marker) Antibody, IgG3, Clone: [ARG1/1125+ ARG1/1126], Mouse, Monoclonal

Artikelnummer: NBT-383-MSM3-P1
Artikelname: Arginase 1 (Hepatocellular Carcinoma Marker) Antibody, IgG3, Clone: [ARG1/1125+ ARG1/1126], Mouse, Monoclonal
Artikelnummer: NBT-383-MSM3-P1
Hersteller Artikelnummer: 383-MSM3-P1
Alternativnummer: NBT-383-MSM3-P1-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human
Immunogen: Recombinant human ARG1 protein fragment (around aa11-97) (exact sequence is proprietary)
Alternative Synonym: Arginase 1, ARG1, liver-type arginase, type I arginase
Recognizes a protein of 35-38kDa, which is identified as Arginase 1 (ARG1). Arginase is a manganese metallo-enzyme that catalyzes the hydrolysis of arginine to generate ornithine and urea. Arginase I and II are isoenzymes, which differ in subcellular localization, regulation, and possibly function. Arginase I is a cytosolic enzyme, which is expressed mainly in the liver as part of the urea cycle, whereas arginase II is a mitochondrial protein found in a variety of tissues. Antibody to ARG-1 labels hepatocytes in normal tissues and granulocytes in peripheral blood. ARG-1 is a sensitive and specific marker for identification of hepatocellular carcinoma.
Klonalität: Monoclonal
Klon-Bezeichnung: [ARG1/1125+ ARG1/1126]
Molekulargewicht: 35-38kDa
Isotyp: IgG3
NCBI: 383
UniProt: P05089
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-paraffin human Hepatocellular Carcinoma stained with ARG1 Mouse Monoclonal Antibody (ARG1/1125 + ARG1/1126).
Formalin-paraffin human Hepatocellular Carcinoma stained with ARG1 Mouse Monoclonal Antibody (ARG1/1125 + ARG1/1126).