Cytokeratin 18 (KRT18) Antibody, IgG1, Clone: [KRT18/835], Mouse, Monoclonal

Produktübersicht

• Artikelname: Cytokeratin 18 (KRT18) Antibody, IgG1, Clone: [KRT18/835], Mouse, Monoclonal
• Artikelnummer: NBT-3875-MSM5-P1ABX
• Hersteller Artikelnummer: 3875-MSM5-P1ABX
• Alternativnummer: NBT-3875-MSM5-P1ABX-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant full-length human KRT18 protein
• Alternative Synonym: Cell Proliferation-inducing Gene 46 Protein, CK18, CYK18Cytokeratin Endo B, K18, Keratin-18, Kerd, KRT18

Produktbeschreibung

This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It is reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [KRT18/835]
• Molekulargewicht: 45kDa
• Isotyp: IgG1
• NCBI: 3875
• UniProt: P05783
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Anwendungsbeschreibung: Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes

Bilder

Formalin-fixe

Formalin-fixed, paraffin-embedded human Lung Cancer stained with Cytokeratin 18 Mouse Monoclonal Antibody (KRT18/835).

Formalin-fixed, paraffin-embedded human Thyroid Cancer stained with Cytokeratin 18 Mouse Monoclonal Antibody (KRT18/835).

Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with Cytokeratin 18 Mouse Monoclonal Antibody (KRT18/835).

Formalin-fixed, paraffin-embedded human Bladder Carcinoma stained with Cytokeratin 18 Mouse Monoclonal Antibody (KRT18/835).

Confocal immunofluorescence image of MCF cells using Cytokeratin 18 Mouse Monoclonal Antibody (KRT18/835) Green (CF488) and Reddot is used to label the nuclei.

SDS-PAGE Analysis Purified Cytokeratin 18 Mouse Monoclonal Antibody (KRT18/835). Confirmation of Integrity and Purity of Antibody.

Formalin-fixed, paraffin-embedded human Prostate Cancer stained with Cytokeratin 18 Mouse Monoclonal Antibody (KRT18/835).

Western Blot Analysis of human HCT116 cell lysate using Cytokeratin 18 Mouse Monoclonal Antibody (KRT18/835).