MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 Antibody, IgG1, Clone: [OJ79c], Mouse, Monoclonal

Produktübersicht

• Artikelname: MCAM (Melanoma Cell Adhesion Molecule) / MUC18 / CD146 Antibody, IgG1, Clone: [OJ79c], Mouse, Monoclonal
• Artikelnummer: NBT-4162-MSM1-P1
• Hersteller Artikelnummer: 4162-MSM1-P1
• Alternativnummer: NBT-4162-MSM1-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FC, IF
• Spezies Reaktivität: Human
• Immunogen: Recombinant full-length human MUC18 protein
• Alternative Synonym: Cell Surface Glycoprotein MUC18, Cell Surface Glycoprotein P1H12, Gicerin, Melanoma Adhesion Molecule (MCAM), Melanoma Associated Glycoprotein MUC18, Melanoma Cell Adhesion Molecule, Melanoma-associated Antigen A32, Mel-CAM, S-endo 1 Endothelial-associated Antigen, Sendo1

Produktbeschreibung

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [OJ79c]
• Molekulargewicht: 130kDa
• Isotyp: IgG1
• NCBI: 4162
• UniProt: P43121
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

SDS-PAGE Analysis of PurifiedCD146 Mouse Monoclonal Antibody (OJ79c). Confirmation of Purity and Integrity of Antibody.