Ki-67 (Proliferating Cell Marker) Antibody, IgG2b, Clone: [MKI67/6571], Mouse, Monoclonal

Artikelnummer: NBT-4288-MSM21-P0
Artikelname: Ki-67 (Proliferating Cell Marker) Antibody, IgG2b, Clone: [MKI67/6571], Mouse, Monoclonal
Artikelnummer: NBT-4288-MSM21-P0
Hersteller Artikelnummer: 4288-MSM21-P0
Alternativnummer: NBT-4288-MSM21-P0-20
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human
Immunogen: Recombinant human Ki67 protein fragment (around aa 2293-2478) (exact sequence is proprietary)
Alternative Synonym: KI-67, Ki67, KI-67 Antigen (KIA), MKI67, Proliferation related Ki-67 antigen
Ki-67 antigen is a nuclear, non-histone protein that is present in all stages of the cell cycle except G0. This characteristic makes Ki-67 an excellent marker for proliferating cells and is commonly used as one of the prognostic factors in cancer studies. A correlation has been demonstrated between Ki-67 index and the histo-pathological grade of neoplasms. Assessment of Ki-67 expression in renal and ureter tumors shows a correlation between tumor proliferation and disease progression, thus making it possible to differentiate high-risk patients. Ki-67 expression may also prove to be important for distinguishing between malignant and benign peripheral nerve sheath tumors. Ki-67 labeling index has been shown to be a prognostic marker in a number of neoplasms including grade II astrocytoma, oligodendroglioma, colon carcinoma, and breast carcinoma. In general, Ki-67 is a good marker of proliferating cell populations. OO
Klonalität: Monoclonal
Klon-Bezeichnung: [MKI67/6571]
Molekulargewicht: 345kDa and 395kDa
Isotyp: IgG2b
NCBI: 4288
UniProt: P46013
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human tonsil stained with Ki67 Mouse Monoclonal Antibody (MKI67/6571). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.
SDS-PAGE Analysis of Purified Ki67 Mouse Monoclonal Antibody (MKI67/6571). Confirmation of Purity and Integrity of Antibody.