Recombinant Myeloperoxidase / MPO Antibody, IgG1, Clone: [rMPO/8694], Mouse, Monoclonal

Artikelnummer: NBT-4353-MSM11-P1ABX
Artikelname: Recombinant Myeloperoxidase / MPO Antibody, IgG1, Clone: [rMPO/8694], Mouse, Monoclonal
Artikelnummer: NBT-4353-MSM11-P1ABX
Hersteller Artikelnummer: 4353-MSM11-P1ABX
Alternativnummer: NBT-4353-MSM11-P1ABX-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant fragment (around aa150-250) of human MPO protein (exact sequence is proprietary)
Alternative Synonym: 84 kDa / 89 kDa myeloperoxidase, EC 1.11.1.7, EC1.11.2.2, fj80f04, MPO, mpx, myeloid-specific peroxidase, Myeloperoxidase, Myeloperoxidase heavy chain, Myeloperoxidase light chain
Myeloperoxidase (MPO) also called the peroxidase (POD), is an important marker of bone marrow cells. It is one of the members of the family of heme peroxidase super existing in myeloid cells (mainly neutrophils and monocytes of aniline blue particles). With the deepening of the research on MPO, MPO gene polymorphism has been found to lead to individual for some disease susceptibility differences, with a variety of human development is closely related to the occurrence of diseases. The antibody reacts with neutrophil granulocytes and monocytes in blood and with precursors of granulocytes in the bone marrow. The antibody is useful as an aid for classification of neoplastic tissue, i.e. myeloblasts and immature myeloid cells of acute myelogenous leukemia, progranulocytic leukemia, monomyelocytic leukemia, erythroleukemia and myeloblastoma.
Klonalität: Monoclonal
Klon-Bezeichnung: [rMPO/8694]
Molekulargewicht: heavy-light promoter: 72kDa, dimer: 140kDa
Isotyp: IgG1
NCBI: 4353
UniProt: P05164
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Recombinant Monoclonal Antibody
Anwendungsbeschreibung: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),Optimal dilutio
Myeloperoxidase
Formalin-fixed, paraffin-embedded human spleen stained with MPO Recombinant Mouse Monoclonal Antibody (rMPO/8694). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.