MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) Antibody, IgG2a, Clone: [MUC1/520], Mouse, Monoclonal

Produktübersicht

• Artikelname: MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) Antibody, IgG2a, Clone: [MUC1/520], Mouse, Monoclonal
• Artikelnummer: NBT-4582-MSM18-P1ABX
• Hersteller Artikelnummer: 4582-MSM18-P1ABX
• Alternativnummer: NBT-4582-MSM18-P1ABX-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human, Mouse
• Immunogen: Human milk-fat globule membranes (HMFGM)
• Alternative Synonym: Breast carcinoma-associated antigen DF3, CA15-3, Carcinoma-associated mucin Episialin, Epithelial Membrane Antigen, H23AG, KL-6, MAM6, MUC-1, MUC-1/SEC, MUC-1/X, MUC1-alpha, MUC1-beta, MUC1-CT, MUC1-NT, MUC1/ZD, Mucin 1 cell surface associated, Mucin-1 subunit beta, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor-associated epithelial membrane antigen, Tumor-associated mucin

Produktbeschreibung

In Western blotting, it recognizes proteins in MW range of 265-400kDa, identified as different glycoforms of EMA. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinomas. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [MUC1/520]
• Molekulargewicht: 265-400kDa
• Isotyp: IgG2a
• NCBI: 4582
• UniProt: P15941
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Monoclonal Antibody

Anwendungsbeschreibung

• Anwendungsbeschreibung: Immunohistology (Formalin-fixed) (0.5-1.0ug/ml for 30 min at RT),(Staining of formalin-fixed tissues requires boiling tissue sections in 10mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes),Optimal dilution for a specific

Bilder

Formalin-fixed, paraffin-embedded human Ovarian Carcinoma stained with MUC-1 / CA15-3 / EMA Mouse Monoclonal Antibody (MUC1/520).

Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with MUC-1 / CA15-3 / EMA Mouse Monoclonal Antibody (MUC1/520).

Formalin-fixed, paraffin-embedded human Endometrial Carcinoma stained with MUC-1 / CA15-3 / EMA Mouse Monoclonal Antibody (MUC1/520).

Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with MUC-1 / EMA Mouse Monoclonal Antibody (MUC1/520)

Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with MUC-1 / EMA Mouse Monoclonal Antibody (MUC1/520).

Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with MUC-1 / EMA Mouse Monoclonal Antibody (MUC1/520).

SDS-PAGE Analysis Purified MUC-1 / EMA Mouse Monoclonal Antibody (MUC1/520). Confirmation of Integrity and Purity of Antibody

Western Blot Analysis of human MCF-7 cell lysate using MUC-1 / EMA Mouse Monoclonal Antibody (MUC1/520).

Western Blot Analysis of Human Kidney, Mouse Kidney, Rat Kidney, Hamster Kidney, Guinea pig Kidney, Rabbit Kidney, Human Lung, Mouse Lung, Rat Lung, Hamster Lung, Guinea pig Lung and Rabbit Lung tissue lysates using MUC-1 Mouse Monoclonal Antibody (MUC1/520).