MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) Antibody, Clone: [GP1.4 + E29], Mouse, Monoclonal

Produktübersicht

• Artikelname: MUC1 / CA15-3 / EMA / CD227 (Epithelial Marker) Antibody, Clone: [GP1.4 + E29], Mouse, Monoclonal
• Artikelnummer: NBT-4582-MSM3-P1
• Hersteller Artikelnummer: 4582-MSM3-P1
• Alternativnummer: NBT-4582-MSM3-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Human milk fat globule membranes (GP1.4), Delipidated extract of human milk fat globule membranes (E29)
• Alternative Synonym: Breast carcinoma-associated antigen DF3, CA15-3, Carcinoma-associated mucin Episialin, Epithelial Membrane Antigen, H23AG, KL-6, MAM6, MUC-1, MUC-1/SEC, MUC-1/X, MUC1-alpha, MUC1-beta, MUC1-CT, MUC1-NT, MUC1/ZD, Mucin 1 cell surface associated, Mucin-1 subunit beta, Peanut-reactive urinary mucin, PEM, PEMT, Polymorphic epithelial mucin, PUM, Tumor-associated epithelial membrane antigen, Tumor-associated mucin

Produktbeschreibung

In Western blotting, it recognizes proteins in MW range of 265-400kDa, identified as different glycoforms of EMA. The alpha subunit has cell adhesive properties. It can act both as an adhesion and an anti-adhesion protein. EMA may provide a protective layer on epithelial cells against bacterial and enzyme attack. The beta subunit contains a C-terminal domain, which is involved in cell signaling, through phosphorylations and protein-protein interactions.In immunohistochemical assays, it superbly stains routine formalin/paraffin carcinoma tissues. Antibody to EMA is useful as a pan-epithelial marker for detecting early metastatic loci of carcinoma in bone marrow or liver.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [GP1.4 + E29]
• Molekulargewicht: 265-400kDa
• NCBI: 4582
• UniProt: P15941
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Formalin-fixed, paraffin-embedded human Colon Carcinoma stained with MUC-1 Mouse Monoclonal Antibody (GP1.4 + E29)

SDS-PAGE Analysis of Purified MUC-1 Mouse Monoclonal Antibody (GP1.4 + E29). Confirmation of Integrity and Purity of Antibody