MUC6 (Mucin 6 / Gastric Mucin) Antibody, IgG1, Clone: [SPM598], Mouse, Monoclonal

Produktübersicht

• Artikelname: MUC6 (Mucin 6 / Gastric Mucin) Antibody, IgG1, Clone: [SPM598], Mouse, Monoclonal
• Artikelnummer: NBT-4588-MSM1X-P1
• Hersteller Artikelnummer: 4588-MSM1X-P1
• Alternativnummer: NBT-4588-MSM1X-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FC, IF, IHC
• Spezies Reaktivität: Human
• Immunogen: A synthetic peptide of the Gastric Mucin 6 tandem repeat sequence
• Alternative Synonym: Gastric mucin 6, MUC6, MUC6 mucin, Mucin 6 oligomeric mucus/gel forming, Mucin glycoprotein Fragment, Mucin-6, Secretory mucin MUC6

Produktbeschreibung

The MUC6 gastric mucin is a secreted glycoprotein that plays an essential role in epithelial cyto-protection from acid, proteases, pathogenic microorganisms, and mechanical trauma in the gastrointestinal tract. Mucin 6 expression is highest in the stomach and gall bladder, with lower expression in the terminal ileum and right colon. In gastric cancer, Mucin 6 has an altered expression. In normal stomach, Mucin 6 is associated with Lewis type 2, Mucin 6 is also expressed in gastric metaplasia, duodenum and pancreas. Mucin 6 is a secretory mucin, located in the deeper mucosal folds of human gall bladder, and its expression is altered with increasing degrees of inflammation.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [SPM598]
• Molekulargewicht: 252kDa
• Isotyp: IgG1
• NCBI: 4588
• UniProt: Q6W4X9
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Formalin-fixed, paraffin-embedded human Gastric Carcinoma stained with MUC6 Monoclonal Antibody (SPM598).