Recombinant PAX7 (Rhabdomyosarcoma Marker) Antibody, IgG2b, Clone: [rPAX7/9325], Mouse, Monoclonal

Produktübersicht

• Artikelname: Recombinant PAX7 (Rhabdomyosarcoma Marker) Antibody, IgG2b, Clone: [rPAX7/9325], Mouse, Monoclonal
• Artikelnummer: NBT-5081-MSM6-P0
• Hersteller Artikelnummer: 5081-MSM6-P0
• Alternativnummer: NBT-5081-MSM6-P0-20
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment (aa301-505) of human PAX7 protein (exact sequence is proprietary)
• Alternative Synonym: HUP1, Paired box gene 7, Paired box homeotic gene 7, Paired domain gene HuP1, PAX7 transcriptional factor, PAX7/FKHR fusion gene, PAX7B, RMS2

Produktbeschreibung

The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [rPAX7/9325]
• Molekulargewicht: 57kDa
• Isotyp: IgG2b
• NCBI: 5081
• UniProt: P23759
• Formulierung: 200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

SDS-PAGE Analysis of Purified PAX7 Recombinant Mouse Monoclonal Antibody (rPAX7/9325). Confirmation of Integrity and Purity of Antibody.