Proteolipid Protein / Myelin PLP Antibody, IgG2a, Clone: [PLP1/4259], Mouse, Monoclonal

Artikelnummer: NBT-5354-MSM1-P1ABX
Artikelname: Proteolipid Protein / Myelin PLP Antibody, IgG2a, Clone: [PLP1/4259], Mouse, Monoclonal
Artikelnummer: NBT-5354-MSM1-P1ABX
Hersteller Artikelnummer: 5354-MSM1-P1ABX
Alternativnummer: NBT-5354-MSM1-P1ABX-100
Hersteller: NeoBiotechnologies
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Bovine, Human, Mouse, Rat, Reptile
Immunogen: Synthetic peptide GRGTKF that recognizes the C terminal region (aa272-277) of myelin proteolipid protein.
Alternative Synonym: Myelin proteolipid protein, PLP, Lipophilin, PLP1, HLD1, SPG2, PMD, Major myelin proteolipid protein (MMPL), DM20
Proteolipid protein (PLP) is the major myelin protein of the CNS and plays an important role in the formation and maintenance of myelin. PLP may play a role in the compaction and stabilization of myelin sheaths, as well as in oligodendrocyte development and axonal survival. Mutations in PLP gene can lead to dysmyelinating diseases. Clone PLP1/4259 is used in the detection of PLP by various analysis methods.
Klonalität: Monoclonal
Klon-Bezeichnung: [PLP1/4259]
Molekulargewicht: 23-25kDa
Isotyp: IgG2a
NCBI: 5354
UniProt: P60201
Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type: Monoclonal Antibody
Anwendungsbeschreibung: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95 &degC followed by cooling at RT for 20 minutes),Optimal diluti
Formalin-fixed, paraffin-embedded human brain stained with Myelin PLP Mouse Monoclonal Antibody (PLP1/4259).
SDS-PAGE Analysis of Purified Myelin PLP Mouse Monoclonal Antibody (PLP1/4259). Confirmation of Integrity and Purity of Antibody.