Recombinant Prostate Specific Acid Phosphatase (PSAP) Antibody, IgG1, Clone: [rACPP/1338], Mouse, Monoclonal

Produktübersicht

• Artikelname: Recombinant Prostate Specific Acid Phosphatase (PSAP) Antibody, IgG1, Clone: [rACPP/1338], Mouse, Monoclonal
• Artikelnummer: NBT-55-MSM4-P1
• Hersteller Artikelnummer: 55-MSM4-P1
• Alternativnummer: NBT-55-MSM4-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant full-length human ACPP protein
• Alternative Synonym: 5-nucleotidase (5-NT), Acid phosphatase prostate, ACP3, Ecto-5-nucleotidase, Prostatic acid phosphatase (PAP), Prostatic acid phosphatase, Thiamine monophosphatase (TMPase)

Produktbeschreibung

Recognizes a protein of 52kDa, identified as prostate specific acid phosphatase (PSAP). This enzyme catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland.PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [rACPP/1338]
• Molekulargewicht: 52kDa
• Isotyp: IgG1
• NCBI: 55
• UniProt: P15309
• Formulierung: 200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Formalin-fixed, paraffin-embedded human Prostate Carcinoma stained with PSAP Mouse Recombinant Monoclonal Antibody (rACPP/1338).

SDS-PAGE Analysis of Purified PSAP Mouse Monoclonal Antibody (rACPP/1338). Confirmation of Purity and Integrity of Antibody.

Analysis of Protein Array containing >19,000 full-length human proteins using PSAP Mouse Monoclonal Antibody (rACPP/1338) Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5. For example, if a Monoclonal Antibody binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that Monoclonal Antibody to protein X is equal to 29.