Recombinant PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein) Antibody, IgG1, Clone: [rPMEPA1/6422], Mouse, Monoclonal

Produktübersicht

• Artikelname: Recombinant PMEPA1 / TMEPAI (Tumor Suppressor Oncoprotein) Antibody, IgG1, Clone: [rPMEPA1/6422], Mouse, Monoclonal
• Artikelnummer: NBT-56937-MSM12-P0
• Hersteller Artikelnummer: 56937-MSM12-P0
• Alternativnummer: NBT-56937-MSM12-P0-20,NBT-56937-MSM12-P0-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant full-length human PMEPA1 protein
• Alternative Synonym: PMEPA, PMEPA1, Prostate transmembrane protein, androgen induced 1, Solid tumor-associated 1 protein, STAG1, TMEPAI, Transmembrane prostate androgen-induced protein, Transmembrane, prostate androgen induced RNA

Produktbeschreibung

PMEPA1 (prostate transmembrane protein, androgen induced 1 is a 287 amino acid single-pass membrane protein that contains WW-binding motifs and localizes to the cell membrane. Expressed at high levels in prostate, kidney and ovary, PMEPA1 interacts with NEDD4 and may play a role in regulating AR (androgen receptor) levels, specifically in prostate cells. Down regulation of PMEPA1 is observed in prostate tumors, suggesting that PMEPA1 may exhibit activity as a tumor suppressor. Overexpression of this protein may play a role in multiple types of cancer.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [rPMEPA1/6422]
• Molekulargewicht: 32kDa
• Isotyp: IgG1
• NCBI: 56937
• UniProt: Q969W9
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Recombinant Monoclonal Antibody

Anwendungsbeschreibung

• Anwendungsbeschreibung: Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT),(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95&degC followed by cooling at RT for 20 minutes),Optimal dilutio

Bilder

Formalin-fixed, paraffin-embedded human colon carcinoma stained with PMEPA1 Recombinant Mouse Monoclonal (rPMEPA1/6422).

Formalin-fixed, paraffin-embedded human prostate stained with PMEPA1 Recombinant Mouse Monoclonal (rPMEPA1/6422).

SDS-PAGE Analysis of Purified PMEPA1 Recombinant Mouse Monoclonal (rPMEPA1/6422). Confirmation of Purity and Integrity of Antibody.

Western Blot Analysis of HeLa cell lysate using PMEPA1 / TMEPAI Recombinant Mouse Monoclonal Antibody (r-+-u-i-+-e1/6422).