Retinol Binding Protein (RBP) Antibody, IgG1, Clone: [SPM442], Mouse, Monoclonal
Artikelnummer:
NBT-5947-MSM1X-P0
Hersteller Artikelnummer:
5947-MSM1X-P0
Alternativnummer:
NBT-5947-MSM1X-P0-20,NBT-5947-MSM1X-P0-100
Hersteller:
NeoBiotechnologies
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IF, IHC, WB
Spezies Reaktivität:
Goat, Human, Monkey, Mouse, Rabbit, Rat
Immunogen:
Retinol binding protein Purified from human plasma
Alternative Synonym:
Cellular retinol-binding protein I, CRBP1, CRBP2, RBP1, RBP2, RBP4, RBPC, Retinol binding protein 1, Retinol binding protein 1 cellular, Retinol binding protein 2 cellular, Retinol binding protein 4 plasma
Recognizes a protein of 21kDa-25kDa, identified as retinol binding protein (RBP). Its epitope localizes between aa 74-182 of human RBP. This MAb recognizes reduced and carboxy-methylated RBP (RCM-RBP) as well as the circulatory RBP but not the native RBP, thereby suggesting that its epitope becomes accessible either on unfolding or upon binding of RBP to transthyretin (prealbumin). RBP is responsible for distributing retinol from the retinoid stores in the liver to the various target tissues. Once secreted into the blood with bound retinol, the vitamin carrier circulates complexed with transthyretin prior to vitamin delivery at the plasma membrane through a receptor-mediated mechanism.
200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Antibody Type:
Monoclonal Antibody
Anwendungsbeschreibung:
Immunofluorescence (1-2ug/ml), Western Blot (1-2ug/ml), Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C follo
Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with RBP1 (SPM442)
Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with RBP1 (SPM442)
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