Recombinant fragment (around aa 1-200) of human S100A4 protein (exact sequence is proprietary)
Alternative Synonym:
S100A4, S100 calcium-binding protein A4, Calvasculin, CAPL, Fibroblast specific protein 1 (FSP1), Leukemia multidrug resistance associated protein, Malignant transformation suppression 1 (MTS1), Metastasin, Placental calcium-binding protein
S100A4 belongs to the S100 super-family of proteins containing 2 EF-hand calcium-binding domains. S100 genes include at least 25 members, including S100A1-S100A18, trichohyalin, filaggrin, repetin, S100P, and S100Z. S100A4 exerts its function via direct interaction with a number of proteins including P53, P63, non-muscle myosin IIA, (TM)6A°a4 integrin, and liprin b1. S100A4 is overexpressed in highly metastatic cancers, which makes it useful as a marker of tumor progression.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
Formalin-fixed, paraffin-embedded human placenta stained with S100A4 Mouse Monoclonal Antibody (S100A4/1481).
Immunofluorescence staining of HeLa cells using S100A4 Mouse Monoclonal Antibody (S100A4/1481) followed by goat anti-mouse IgG-CF488 (green). Nuclei stained with RedDot.
Flow Cytometric Analysis of T98G cells using S100A4 Mouse Monoclonal Antibody (S100A4/1481) followed by goat anti-mouse IgG-CF488 (blue), isotype control (red).
Flow Cytometric Analysis of A549 cells using S100A4 Mouse Monoclonal Antibody (S100A4/1481) followed by goat anti-mouse IgG-CF488 (blue), isotype control (red).
Western blot analysis of HeLa, A549 and A375 cell lysates using S100A4 Mouse Monoclonal Antibody (S100A4/1481).
Western Blot Analysis of HeLa cell lysate using S100A4 Mouse Monoclonal Antibody (S100A4/1481).
SDS-PAGE Analysis Purified S100A4 Mouse Monoclonal Antibody (S100A4/1481). Confirmation of Integrity and Purity of Antibody.
Analysis of Protein Array containing more than 19,000 full-length human proteins using S100A4 Mouse Monoclonal Antibody (S100A4/1481). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SD&apos,s) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD&apos,s) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.
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