Recombinant fragment (around aa1-95) of human MIG9 protein (exact sequence is proprietary)
Alternative Synonym:
Migration inducing gene 9 (MIG9), S100E, S100 calcium binding protein P
S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis and invasion through the binding of Ca2+ ions, receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein and cathepsin D.S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could potentially serve as diagnostic marker, prognostic/predictive indicator and therapy target for different carcinomas.
200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified S100P Recombinant Rabbit Monoclonal Antibody (S100P/7978R). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human bladder stained with S100P Recombinant Rabbit Monoclonal Antibody (S100P/7978R). Inset: PBS instead of primary antibody, secondary only negative control.
