CXCR5 (Marker of T Follicular Helper (Tfh) Cells) Antibody, IgG2b, Clone: [CXCR5/13100], Mouse, Monoclonal

Produktübersicht

• Artikelname: CXCR5 (Marker of T Follicular Helper (Tfh) Cells) Antibody, IgG2b, Clone: [CXCR5/13100], Mouse, Monoclonal
• Artikelnummer: NBT-643-MSM10-P1ABX
• Hersteller Artikelnummer: 643-MSM10-P1ABX
• Alternativnummer: NBT-643-MSM10-P1ABX-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment of human CXCR5 protein (exact sequence is proprietary)
• Alternative Synonym: BLR1, Burkitt lymphoma receptor 1, GTP binding protein (chemokine (C-X-C motif) receptor 5), CD185 antigen, Chemokine receptor 5, CXC chemokine receptor type 5, MDR 15, MDR15, MGC117347, Monocyte derived receptor 15

Produktbeschreibung

Burkitts lymphoma receptor 1 (Blr1) is a lymphocyte specific chemokine receptor expressed at low levels in secondary lymphoid tissues and in defined structures of the cerebellum. The G protein-coupled receptor has significant homology to other chemokine receptors. Stimulation of Blr1 by its ligand, B-lymphocyte chemoattractant (BLC) results in an influx of calcium into the cell and the chemotaxis of the cell. Blr1 is required for B-cell migration into splenic and Peyer s patch follicles. BLC expression in Peyer s patches is highest in germinal centers, where B cells undergo somatic mutation and affinity maturation.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [CXCR5/13100]
• Molekulargewicht: 56kDa
• Isotyp: IgG2b
• NCBI: 643
• UniProt: P32302
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

SDS-PAGE Analysis of Purified CXCR5 Mouse Monoclonal Antibody (CXCR5/13100). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human adrenal gland stained with CXCR5 Mouse Monoclonal Antibody (CXCR5/13100). Inset: PBS instead of primary antibody, secondary only negative control.

Formalin-fixed, paraffin-embedded human brain stained with CXCR5 Mouse Monoclonal Antibody (CXCR5/13100). Inset: PBS instead of primary antibody, secondary only negative control.