SLC18A2 Antibody, IgG2, Clone: [SLC18A2/7983], Mouse, Monoclonal

Produktübersicht

• Artikelname: SLC18A2 Antibody, IgG2, Clone: [SLC18A2/7983], Mouse, Monoclonal
• Artikelnummer: NBT-6571-MSM3-P0
• Hersteller Artikelnummer: 6571-MSM3-P0
• Alternativnummer: NBT-6571-MSM3-P0-20
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment of human SLC18A2 protein (exact sequence is proprietary)
• Alternative Synonym: MNAT, Monoamine neurotransmitter transporter, Monoamine transporter, SLC18A2, Solute carrier family 18 (vesicular monoamine) member 2, SVAT, SVMT, Synaptic vesicle monoamine transporter brain, VAT2, Vesicle monoamine/H+ antiporter, Vesicular monoamine transporter 2, VMAT2

Produktbeschreibung

Neurotransmission depends on the regulated exocytotic release of chemical transmitter molecules. This requires the packaging of these substances into the specialized secretory vesicles of neurons and neuroendocrine cells, a process mediated by specific vesicular transporters. The family of genes encoding the vesicular transporters of monoamines (VMAT 1 and VMAT 2) and acetylcholine (VACht) have been cloned and functionally characterized. The sequence of these integral membrane proteins predicts twelve transmembrane domains and weak homology to a class of bacterial antibiotic resistance proteins. The vesicular transport of neurotransmitter molecules has been shown to be an active ATP- and proton dependent transport mechanism.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [SLC18A2/7983]
• Molekulargewicht: 63kDa
• Isotyp: IgG2
• NCBI: 6571
• UniProt: Q05940
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

SDS-PAGE Analysis of Purified SLC18A2 Mouse Monoclonal Antibody (SLC18A2/7983). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human prostate stained with SLC18A2 Mouse Monoclonal Antibody (SLC18A2/7983). HIER: Tris/EDTA, pH9.0, 45min. 2°C: HRP-polymer, 30min. DAB, 5min.

Formalin-fixed, paraffin-embedded human brain stained with SLC18A2 Mouse Monoclonal Antibody (SLC18A2/7983). Inset: PBS instead of primary antibody, secondary only negative control.