CD147 / BSG / EMMPRIN / Neurothelin Antibody, IgG1, Clone: [8D6], Mouse, Monoclonal

Produktübersicht

• Artikelname: CD147 / BSG / EMMPRIN / Neurothelin Antibody, IgG1, Clone: [8D6], Mouse, Monoclonal
• Artikelnummer: NBT-682-MSM1-P1
• Hersteller Artikelnummer: 682-MSM1-P1
• Alternativnummer: NBT-682-MSM1-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FC, IF, IHC, WB
• Spezies Reaktivität: Human
• Immunogen: Human T cell line Molt 13
• Alternative Synonym: 5A11 Antigen, 5F7, Basigin, Blood brain barrier HT7 antigen BSG, Extracellular Matrix Metalloproteinase Inducer (EMMPRIN), Leukocyte Activation Antigen M6, Neurothelin, OK Blood Group Antigen, TCSF, Tumor Cell-derived Collagenase Stimulatory Factor

Produktbeschreibung

This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [8D6]
• Molekulargewicht: 35kDa (non-reduced), 40kDa (reduced)
• Isotyp: IgG1
• NCBI: 682
• UniProt: P35613
• Formulierung: 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Formalin-fixed, paraffin-embedded human renal cell carcinoma stained with CD147 Mouse Monoclonal Antibody (8D6).

SDS-PAGE Analysis of Purified CD147 Mouse Monoclonal Antibody (8D6). Confirmation of Integrity and Purity of Antibody.

Western Blot Analysis of HepG2 lysate using CD147 Mouse Monoclonal Antibody (8D6).