Recombinant CD147 / BSG / EMMPRIN / Neurothelin Antibody, IgG1, Clone: [rAB1843], Mouse, Monoclonal

Produktübersicht

• Artikelname: Recombinant CD147 / BSG / EMMPRIN / Neurothelin Antibody, IgG1, Clone: [rAB1843], Mouse, Monoclonal
• Artikelnummer: NBT-682-MSM26-P1ABX
• Hersteller Artikelnummer: 682-MSM26-P1ABX
• Alternativnummer: NBT-682-MSM26-P1ABX-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant human BSG protein
• Alternative Synonym: 5A11 Antigen, 5F7, Basigin, Blood brain barrier HT7 antigen BSG, Extracellular Matrix Metalloproteinase Inducer (EMMPRIN), Leukocyte Activation Antigen M6, Neurothelin, OK Blood Group Antigen, TCSF, Tumor Cell-derived Collagenase Stimulatory Factor

Produktbeschreibung

This MAb recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It is expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. It stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [rAB1843]
• Molekulargewicht: 35kDa (non-reduced), 40kDa (reduced)
• Isotyp: IgG1
• NCBI: 682
• UniProt: P35613
• Formulierung: 200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

SDS-PAGE Analysis of Purified CD147 / Basigin Recombinant Mouse Monoclonal Antibody (rAB1843). Confirmation of Purity and Integrity of Antibody.

Formalin-fixed, paraffin-embedded human placenta stained with CD147 / Basigin Recombinant Mouse Monoclonal Antibody (rAB1843). Inset: PBS instead of primary antibody, secondary only negative control.