CD71 / Transferrin Receptor (TFRC) Antibody, IgG1, Clone: [TFRC/1149], Mouse, Monoclonal

Produktübersicht

• Artikelname: CD71 / Transferrin Receptor (TFRC) Antibody, IgG1, Clone: [TFRC/1149], Mouse, Monoclonal
• Artikelnummer: NBT-7037-MSM4-P1
• Hersteller Artikelnummer: 7037-MSM4-P1
• Alternativnummer: NBT-7037-MSM4-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant human TFRC protein
• Alternative Synonym: Mtvr-1, p90, TFR1, TFRC transferrin receptor (p90 CD71), TRFR

Produktbeschreibung

It recognizes a ~90-95kDa protein which is identified as cell surface transferrin receptor (CD71), a disulfide-bonded homodimeric glycoprotein of 180-190kDa. This MAb is highly specific to CD71 and shows no cross-reaction with other related proteins. Ligand for transferrin receptor is the serum iron transport protein, transferrin. This receptor is broadly distributed in carcinomas, sarcomas, leukemias, and lymphomas. CD71/Transferrin receptor has been reported to be associated with cell proliferation in both normal and neoplastic tissues and useful in predicting clinical behavior or response to therapy in a number of malignancies including breast cancer.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [TFRC/1149]
• Molekulargewicht: 85-95kDa (monomer), 190kDa (dimer)
• Isotyp: IgG1
• NCBI: 7037
• UniProt: P02786
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Western Blot of PC3 cell lysate using CD71 Monoclonal Antibody (TFRC/1149)

Western Blot of PC3 cell lysate using CD71 Monoclonal Antibody (TFRC/1149)