TGF-alpha (Transforming Growth Factor alpha) Antibody, IgM, Clone: [SPM542], Mouse, Monoclonal

Produktübersicht

• Artikelname: TGF-alpha (Transforming Growth Factor alpha) Antibody, IgM, Clone: [SPM542], Mouse, Monoclonal
• Artikelnummer: NBT-7039-MSM2X-P1
• Hersteller Artikelnummer: 7039-MSM2X-P1
• Alternativnummer: NBT-7039-MSM2X-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: FC, IF, IHC
• Spezies Reaktivität: Human, Rabbit, Zebrafish
• Immunogen: A 10-amino acid synthetic peptide (aa34-43, PPVAAAVVSH) from human TGFalpha.
• Alternative Synonym: EGF-like TGF, ETGF, TFGA, TGF Type 1, TGFA, Wa1, Waved 1

Produktbeschreibung

This antibody reacts with the TGF alpha and shows no cross-reaction with EGF and the neuropeptide synenkephalin. The staining with this MAb is completely blocked by the peptide used for raising this antibody. TGF (aa50) is a growth factor with 33% homology to EGF, binds to EGFR, activates tyrosine phosphorylation of the receptor, and stimulates cell proliferation. It plays a role in tumor initiation by inducing the reversible transformed phenotype.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [SPM542]
• Molekulargewicht: 6kDa
• Isotyp: IgM
• NCBI: 7039
• UniProt: P01135
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Formalin-fixed, paraffin-embedded human Testicular Carcinoma stained with TGF alpha Monoclonal Antibody (SPM542)