Recombinant Thrombomodulin / CD141 (Endothelial Cell Marker) Antibody, IgG1, Clone: [MSVA-141M], Mouse, Monoclonal

Produktübersicht

• Artikelname: Recombinant Thrombomodulin / CD141 (Endothelial Cell Marker) Antibody, IgG1, Clone: [MSVA-141M], Mouse, Monoclonal
• Artikelnummer: NBT-7056-MSM6-P1
• Hersteller Artikelnummer: 7056-MSM6-P1
• Alternativnummer: NBT-7056-MSM6-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment (around aa 69-194) of human Thrombomodulin (CD141) protein (exact sequence is proprietary)
• Alternative Synonym: AHUS6, BDCA3, CD141, Fetomodulin, Thbd, THPH12, THRM, Thrombomodulin (TM)

Produktbeschreibung

It recognizes a protein of 75kDa, identified as Thrombomodulin. Thrombomodulin is a transmembrane glycoprotein with natural anticoagulant properties. It is normally expressed by a restricted number of cells, such as endothelial and mesothelial cells. In addition, synovial lining and syncytio-trophoblasts of placenta also express thrombomodulin. This protein is present in almost all of benign vascular tumors and majority of malignant vascular tumors (Kaposis sarcoma, angiosarcoma, and epithelioid hemangioendothelioma). Hence, anti-thrombomodulin serves as a sensitive marker for lymphatic endothelial cells and their tumors. Recently, thrombomodulin antibody has been used for mesothelial cells and malignant mesotheliomas.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [MSVA-141M]
• Molekulargewicht: 100kDa
• Isotyp: IgG1
• NCBI: 7056
• UniProt: P07204
• Formulierung: Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide.

Bilder

Thrombomodulin Mouse Recombinant Monoclonal Antibody (MSVA-141M) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.