Recombinant human TLE1 fragment (aa 175-338) (exact sequence is proprietary)
Alternative Synonym:
Enhancer of split groucho 1 (ESG1), Enhancer of split groucho-like protein 1, GRG1, TLE1, Transducin like enhancer of split 1, Transducin-like enhancer protein 1
Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer proteinvC OO1 (TLE1) is a protein that isvC OOencoded by thevC OOTLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.
Ab produced in HEK293 cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide.
Transducin-like enhancer protein 1 Rabbit Recombinant Monoclonal Antibody (MSVA-856R) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.
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