Prokaryotic recombinant protein corresponding to the full length wild type mouse p53 protein
Alternative Synonym:
Antigen NY-CO-13, BCC7, Cellular Tumor Antigen p53, LFS1, TP53, Transformation Related Protein 53 (TRP53)
The accumulation of p53 protein in response to DNA damage in vitro is well established and appears to induce growth arrest and apoptosis by the transcriptional regulation of other genes. In irradiated mice, p53 protein accumulates in splenocytes, thymocytes and osteocytes, though not in hepatocytes. Mouse T3T3 cells express high levels of phenotypically characteristic wild type p53 protein which carries two missense mutations. The range of antigenic sites in mouse p53 protein and human p53 protein is very similar.
200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared i
SDS-PAGE Analysis of Purified p53 Recombinant Mouse Monoclonal Antibody (rIMX25). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human tonsil stained with p53 Recombinant Mouse Monoclonal Antibody (rIMX25). Inset: PBS instead of primary antibody, secondary only negative control.
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