p73 (Tumor Suppressor) Antibody, IgG2b, Clone: [P73/2531], Mouse, Monoclonal

Produktübersicht

• Artikelname: p73 (Tumor Suppressor) Antibody, IgG2b, Clone: [P73/2531], Mouse, Monoclonal
• Artikelnummer: NBT-7161-MSM1-P1
• Hersteller Artikelnummer: 7161-MSM1-P1
• Alternativnummer: NBT-7161-MSM1-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant full-length human TP73 protein
• Alternative Synonym: p53-like transcription factor, p53-related protein, p73, TP73, Tumor protein p73

Produktbeschreibung

The p53 gene is a widely studied anti-oncogene, or tumor suppressor gene. The p53 gene product can act as a negative regulator of cell growth in response to DNA damage. Mutations and allelic loss of the p53 gene have been associated with malignant transformation in a wide variety of human tumors. p53 shares considerable sequence similarity with p73, a gene that maps to a region in chromosome 1 that is frequently deleted in neuroblastomas. However, p73 does not appear to be activated by DNA damaging agents. The p73 isoform p73.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [P73/2531]
• Molekulargewicht: 73kDa
• Isotyp: IgG2b
• NCBI: 7161
• UniProt: O15350
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.

Bilder

Formalin-fixed, paraffin-embedded human Skin stained with p73 Mouse Monoclonal Antibody (P73/2531).

Formalin-fixed, paraffin-embedded human Skin stained with p73 Mouse Monoclonal Antibody (P73/2531).

SDS-PAGE Analysis of Purified p73 Mouse Monoclonal Antibody (P73/2531). Confirmation of Purity and Integrity of Antibody.