GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Antibody, IgG2a, Clone: [HSP90B1/1192], Rat, Monoclonal

Produktübersicht

• Artikelname: GRP94 / HSP90B1 (Endoplasmic Reticulum Marker) Antibody, IgG2a, Clone: [HSP90B1/1192], Rat, Monoclonal
• Artikelnummer: NBT-7184-RTM2-P1
• Hersteller Artikelnummer: 7184-RTM2-P1
• Alternativnummer: NBT-7184-RTM2-P1-100
• Hersteller: NeoBiotechnologies
• Wirt: Rat
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant full-length human HSP90B1 protein
• Alternative Synonym: Glucose Regulated Protein 94, 94kDa glucose-regulated protein, Endoplasmin, Endothelial cell (HBMEC) glycoprotein (ECGP), Heat shock protein 90kDa beta member 1 (HSP90B1), Stress inducible tumor rejection antigen GP96, TRA1, Tumor rejection antigen-1 (gp96)

Produktbeschreibung

Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96). Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90). This MAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grps are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [HSP90B1/1192]
• Molekulargewicht: 94kDa
• Isotyp: IgG2a
• NCBI: 7184
• UniProt: P14625
• Formulierung: 200ug/ml of Ab Purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA at 1.0mg/ml.

Bilder

Formalin-fixed, paraffin-embedded human Breast Carcinoma stained with GRP94 Monoclonal Antibody (HSP90B1/1192).