Recombinant fragment (around aa900-1100) of human TRPS1 protein (exact sequence is proprietary)
Alternative Synonym:
GC79, LGCR, Transcriptional repressor GATA binding 1, Tricho-rhino-phalangeal syndrome type I protein, Trichorhinophalangeal syndrome I, Trichorhinophalangeal syndrome I homolog, TRPS 1, trpS1, TRPS1 gene, TRPS1_HUMAN, Zinc finger protein GC79, Zinc finger transcription factor TRPS 1 antibody
Transcriptional repressor. Binds specifically to GATA sequences and represses expression of GATA-regulated genes at selected sites and stages in vertebrate development. Regulates chondrocyte proliferation and differentiation. Executes multiple functions in proliferating chondrocytes, expanding the region of distal chondrocytes, activating proliferation in columnar cells and supporting the differentiation of columnar into hypertrophic chondrocytes. Ubiquitously expressed in the adult. Found in fetal brain, lung, kidney, liver, spleen and thymus. More highly expressed in androgen-dependent than in androgen-independent prostate cancer cells.
Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide.
Zinc finger transcription factor Trps1 Rabbit Recombinant Monoclonal Antibody (MSVA-512R) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.
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