Recombinant PGP9.5 / UchL1 (pan-Neuronal Marker) Antibody, Clone: [MSVA-905R], Rabbit, Monoclonal

Artikelnummer: NBT-7345-RBM52-P0
Artikelname: Recombinant PGP9.5 / UchL1 (pan-Neuronal Marker) Antibody, Clone: [MSVA-905R], Rabbit, Monoclonal
Artikelnummer: NBT-7345-RBM52-P0
Hersteller Artikelnummer: 7345-RBM52-P0
Alternativnummer: NBT-7345-RBM52-P0-20
Hersteller: NeoBiotechnologies
Wirt: Rabbit
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human
Immunogen: Recombinant full-length human UCHL1 protein
Alternative Synonym: Gracile Axonal Dystrophy, Neuron Cytoplasmic Protein 9.5, Park5, Parkinson Disease 5, PGP95, Protein Gene Product 9.5, Ubiquitin Carboxyl-terminal Esterase L1, Ubiquitin Carboxyl-terminal Hydrolase Isozyme L1, Ubiquitin Thioesterase L1, Ubiquitin Thiolesterase L1
This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinsons disease.
Klonalität: Monoclonal
Klon-Bezeichnung: [MSVA-905R]
Molekulargewicht: 20-30kDa
NCBI: 7345
UniProt: P09936
Formulierung: Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide.
Ubiquitin carboxyl-terminal hydrolase isozyme L1 Rabbit Recombinant Monoclonal Antibody (MSVA-905R) tested on many normal and cancer tissues. The immunohistochemistry staining in these tissues aligns with the expression data in Human Protein Atlas.