Complement component C9 binds to the C5b-8 complex as the final protein of the membrane attack complex. After binding, it undergoes a conformational change and inserts itself into the cell membrane, forming transmembrane channels. Complement component C9 acts in a similar way to perforin, a pore forming protein found in cytotoxic T cells. Male and female reproductive tissues express and synthesize complement components, binding proteins and receptors, although the implications of this are unclear.
200ug/ml of Ab produced in CHO cell mammalian-based expression system. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Analysis of Purified Complement Component C9 Recombinant Mouse Monoclonal Antibody (r10A6). Confirmation of Purity and Integrity of Antibody.
Formalin-fixed, paraffin-embedded human tonsil stained with Complement Component C9 Recombinant Mouse Monoclonal Antibody (r10A6). Inset: PBS instead of primary antibody, secondary only negative control.
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