Recombinant von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Antibody, IgG1, Clone: [rVWF/1465], Mouse, Monoclonal

Produktübersicht

• Artikelname: Recombinant von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Antibody, IgG1, Clone: [rVWF/1465], Mouse, Monoclonal
• Artikelnummer: NBT-7450-MSM8-P1ABX
• Hersteller Artikelnummer: 7450-MSM8-P1ABX
• Alternativnummer: NBT-7450-MSM8-P1ABX-100
• Hersteller: NeoBiotechnologies
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC, WB
• Spezies Reaktivität: Human
• Immunogen: Recombinant fragment of human vWF protein (aa1815-1939) (exact sequence is proprietary)
• Alternative Synonym: Coagulation Factor VIII, Factor VIII Related Antigen, F8VWF, von Willebrand Antigen 2, von Willebrand Disease (vWD)

Produktbeschreibung

von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [rVWF/1465]
• Molekulargewicht: 250kDa
• Isotyp: IgG1
• NCBI: 7450
• UniProt: P04275
• Formulierung: 200ug/ml of recombinant Ab Purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
• Antibody Type: Recombinant Monoclonal Antibody

Anwendungsbeschreibung

• Anwendungsbeschreibung: Western Blot (1-2ug/ml), Immunoprecipitation (0.5-1ug/500ug protein lysate),Immunohistochemistry (Formalin-fixed) (1-2ug/ml for 30 minutes at RT) (Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for

Bilder

SDS-PAGE Analys

Formalin-fixed, paraffin-embedded human Tonsil stained with vWF Recombinant Mouse Monoclonal Antibody (rVWF/1465).

Western Blot Analysis A) Recombinant Protein (B) human lung lysate Using Recombinant Mouse Monoclonal Antibody (rVWF/1465).

SDS-PAGE Analysis of Purified vWF Recombinant Mouse Monoclonal Antibody (rVWF/1465). Confirmation of Purity and Integrity of Antibody.