Recombinant von Willebrand Factor / Factor VIII Related-Ag (Endothelial Marker) Antibody, Clone: [VWF/1859R], Rabbit, Monoclonal
Artikelnummer:
NBT-7450-RBM9-P1
Hersteller Artikelnummer:
7450-RBM9-P1
Alternativnummer:
NBT-7450-RBM9-P1-100
Hersteller:
NeoBiotechnologies
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
IHC, WB
Spezies Reaktivität:
Human
Immunogen:
Recombinant fragment of human vWF protein (aa1815-1939) (exact sequence is proprietary)
Alternative Synonym:
Coagulation Factor VIII, Factor VIII Related Antigen, F8VWF, von Willebrand Antigen 2, von Willebrand Disease (vWD)
von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposis sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.
200ug/ml of recombinant MAb Purified by Protein A. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
SDS-PAGE Anal
Formalin-fixed, paraffin-embedded human Tonsil stained with vWF Rabbit Recombinant Monoclonal Antibody (VWF/1859R).
Western Blot Analysis A) Recombinant Protein (B) human lung lysate Using Rabbit Recombinant Monoclonal Antibody (VWF/1859R).
SDS-PAGE Analysis of Purified Rabbit Recombinant Monoclonal Antibody (VWF/1859R).
* Mehrwertsteuer und Versandkosten nicht enthalten. Irrtümer und Preisänderungen vorbehalten
